Your risk of heart disease may be influenced by the time you go to bed. According to studies, there is a heart-healthy time to fall asleep: between 10 and 11 p.m.

A review of data from over 88 thousand persons observed for six years found that those who fell asleep between 11 and 11:59 pm were at a 12 percent higher risk and people who fell asleep at midnight or later had a 25% increased chance of getting cardiovascular disease.

Getting to sleep before 10 p.m was linked to a 24% increase in risk, According to a study published Monday in the European Heart Journal—Digital Health.

David Plans, a neuroscientist and experimental psychologist said, “The body has a 24-hour internal clock, called circadian rhythm, that helps regulate physical and mental functioning.”

“While the results of our study do not prove causation, they do imply that early or late bedtimes are more likely to upset the body clock, which could have negative effects for cardiovascular health.”

The new study “truly validates what we know from a cardiovascular risk prevention approach — sleep is a risk factor,” said Dr Francoise Marvel, co-director of the Johns Hopkins Digital Health Lab at Johns Hopkins Medicine in Baltimore.

According to the American Heart Association, cardiovascular disease is the leading cause of mortality in the United States.

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